Isomorphic Labs, a Google DeepMind spinoff, unveils IsoDDE, a system that it says surpasses AlphaFold 3 in biomolecular structure prediction and drug discovery
Today, we are excited to share an update on our progress towards a new frontier of drug design. We have unlocked a new paradigm …
Isomorphic Labs
Related Coverage
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- Isomorphic claims major advance with new AI drug design engine, in ‘step change’ versus AlphaFold 3 Endpoints News · Andrew Dunn
- Google's AI drug discovery spinoff Isomorphic Labs claims major leap beyond AlphaFold 3 The Decoder · Matthias Bastian
- We just released a technical report showing our drug design engine consistently outperforming industry benchmarks. … Sarah Skerratt
- Isomorphic Labs IsoDDE vs AlphaFold 3: What's new in the AI drug design engine? Digit · Vyom Ramani
- Isomorphic Labs New AI Doubles AlphaFold 3's Accuracy in Protein-Ligand Predictions WinBuzzer · Markus Kasanmascheff
Discussion
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@demishassabis
Demis Hassabis
on x
The drug design engine we're building at @IsomorphicLabs is extending the SOTA further across key benchmarks, showing huge progress in accuracy and capabilities critical for in-silico drug discovery. Incredible work from @maxjaderberg and the entire team at Isomorphic Labs!
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@kimmonismus
@kimmonismus
on x
The more I read up, the more impressive the breakthrough Isomorphic labs has made here. Isomorphic Labs' IsoDDE doesn't just predict protein structures better than AlphaFold 3, it can find hidden binding pockets in seconds that used to take six months of lab work, and predict how…
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@aosokin_ml
Anton Osokin
on x
So proud of the @IsomorphicLabs team and incredibly privileged to have played a part in building IsoDDE. Huge milestone! 🚀 Check out what we've been working on below.
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@_lychrel
Jack Lynch
on x
Among other things, IsoDDE's binding affinity predictions exceed gold standard physics-based methods—an important step toward AI-driven rational drug design. Grateful to have contributed to this work alongside the Iso team, and hugely excited for the future we're building
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@andrewcurran_
Andrew Curran
on x
Founded by Sir Demis, Isomorphic Labs are continuing their work on AI drug design. From the technical report: 'Our results in structure prediction present the first step-change improvement since the release of AlphaFold 3. They enable structure-based drug design on the most [imag…
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@maxjaderberg
Max Jaderberg
on x
The Iso team has cooked something incredible: our new technical report unveils the latest results from our drug design engine, the IsoDDE, progressing far beyond AlphaFold 3. This breaks new ground compared to AF and other similar methods by a significant degree across all key [i…
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@isomorphiclabs
@isomorphiclabs
on x
Today we share a technical report demonstrating how our drug design engine achieves a step-change in accuracy for predicting biomolecular structures, more than doubling the performance of AlphaFold 3 on key benchmarks and unlocking rational drug design even for examples it has [i…
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@teortaxestex
@teortaxestex
on x
if you forgot, the CEO and founder of Isomorphic is Demis Hassabis. So ByteDance has just caught up (and slightly exceeded) AlphaFold 3, and the original team is... significantly ahead. [image]